Trisomy 21 tilts the balance
S Izraeli - Blood, The Journal of the American Society of …, 2008 - ashpublications.org
Blood, The Journal of the American Society of Hematology, 2008•ashpublications.org
Similarly to the leukemias of DS, sporadic childhood leukemias are initiated in utero.
Somatic structural or numerical chromosomal aberrations acquired in fetal hematopoietic
progenitors initiate the growth of a preleukemic clone. 8 Thus, the relevance of studies, such
as the 2 reported by Tunstall-Pedoe and Chou and their colleagues, extends beyond DS.
They are important for the general understanding of how normal fetal hematopoietic
development is diverted toward leukemia.
Somatic structural or numerical chromosomal aberrations acquired in fetal hematopoietic
progenitors initiate the growth of a preleukemic clone. 8 Thus, the relevance of studies, such
as the 2 reported by Tunstall-Pedoe and Chou and their colleagues, extends beyond DS.
They are important for the general understanding of how normal fetal hematopoietic
development is diverted toward leukemia.
Similarly to the leukemias of DS, sporadic childhood leukemias are initiated in utero. Somatic structural or numerical chromosomal aberrations acquired in fetal hematopoietic progenitors initiate the growth of a preleukemic clone. 8 Thus, the relevance of studies, such as the 2 reported by Tunstall-Pedoe and Chou and their colleagues, extends beyond DS. They are important for the general understanding of how normal fetal hematopoietic development is diverted toward leukemia.
ashpublications.org