Anti-GQ1b antibody does not affect neuromuscular transmission in human limb muscle

S Kuwabara, S Misawa, H Takahashi, S Sawai… - Journal of …, 2007 - Elsevier
Anti-ganglioside GQ1b antibody induces neuromuscular blocking on mouse phrenic nerve–
diaphragm preparations. Several reports suggest that patients with this antibody show
abnormal neuromuscular transmission in the facial or limb muscles, but limb muscle
weakness is unusual in Miller Fisher syndrome that is often associated with anti-GQ1b
antibody. To determine whether anti-GQ1b sera affect neuromuscular transmission in
human limb muscles, axonal-stimulating single fiber electromyography was performed in the …