KSHV sequences in biopsies and cultured spindle cells of epidemic, iatrogenic and Mediterranean forms of Kaposi's sarcoma

MG Aluigi, A Albini, S Carlone, L Repetto… - Research in …, 1996 - Elsevier
The pathogenesis of Kaposi's sarcoma (KS) is still unclear, and several factors appear to be
involved in the onset of the Kaposi's lesion. Epidemiological studies suggest that a common
infective agent may contribute to KS. Sequences which appear to represent a new
gammaherpesvirus, currently termed KSHV/HHV8, have recently been identified in KS. To
further examine the relationship between this virus and KS, we obtained biopsy samples of
KS lesions; these samples, the spindle cells cultured from these lesions and the PBMC of …