Carbon-11 acetate as a tracer of myocardial oxygen consumption
LJ Klein, FC Visser, P Knaapen, JH Peters… - European journal of …, 2001 - Springer
LJ Klein, FC Visser, P Knaapen, JH Peters, GJJ Teule, CA Visser, AA Lammertsma
European journal of nuclear medicine, 2001•SpringerEstimation of myocardial oxygen consumption (MVO 2) and myocardial blood flow (MBF) is
important for the understanding of various (patho) physiological mechanisms and diseases.
Clearance rates of carbon-11 labelled acetate, determined with positron emission
tomography, allow estimation of MVO 2 on a segmental level and non-invasively. In addition,
MBF can be determined from uptake rates. In this review, the background to estimation of
MVO 2 and MBF is discussed, as well as the currently available literature that has used 11 C …
important for the understanding of various (patho) physiological mechanisms and diseases.
Clearance rates of carbon-11 labelled acetate, determined with positron emission
tomography, allow estimation of MVO 2 on a segmental level and non-invasively. In addition,
MBF can be determined from uptake rates. In this review, the background to estimation of
MVO 2 and MBF is discussed, as well as the currently available literature that has used 11 C …
Abstract
Estimation of myocardial oxygen consumption (MVO2) and myocardial blood flow (MBF) is important for the understanding of various (patho)physiological mechanisms and diseases. Clearance rates of carbon-11 labelled acetate, determined with positron emission tomography, allow estimation of MVO2 on a segmental level and non-invasively. In addition, MBF can be determined from uptake rates. In this review, the background to estimation of MVO2 and MBF is discussed, as well as the currently available literature that has used 11C-acetate to estimate MVO2 and MBF.
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