A1 adenosine receptor activation inhibits inflammation, necrosis, and apoptosis after renal ischemia-reperfusion injury in mice
HT Lee, G Gallos, SH Nasr… - Journal of the American …, 2004 - journals.lww.com
It was previously demonstrated that preischemic A 1 adenosine receptor (AR) activation
protects renal function after ischemia-reperfusion (IR) injury in rats. The role of the A 1 AR in
modulating inflammation, necrosis, and apoptosis in the kidney after IR renal injury was
further characterized. C57BL/6 mice were subjected to 30 min of renal ischemia, with or
without pretreatment with 1, 3-dipropyl-8-cyclopentylxanthine or 2-
chlorocyclopentyladenosine (selective A 1 AR antagonist and agonist, respectively). Plasma …
protects renal function after ischemia-reperfusion (IR) injury in rats. The role of the A 1 AR in
modulating inflammation, necrosis, and apoptosis in the kidney after IR renal injury was
further characterized. C57BL/6 mice were subjected to 30 min of renal ischemia, with or
without pretreatment with 1, 3-dipropyl-8-cyclopentylxanthine or 2-
chlorocyclopentyladenosine (selective A 1 AR antagonist and agonist, respectively). Plasma …