Immunohistochemical evaluation of HER-2/neu expression in pancreatic adenocarcinoma and pancreatic intraepithelial neoplasms
JD Day, JA Digiuseppe, C Yeo, M Lai-Goldman… - Human pathology, 1996 - Elsevier
Although several morphological and molecular genetic studies have implicated various
grades of pancreatic duct hyperplasia as precursor lesions to infiltrating pancreatic
adenocarcinoma, the identity of preinvasive pancreatic neoplasms remains controversial. In
the present study, the authors examined the expression of the epidermal growth factor
receptor homologue, HER-2/neu (c-erbB-2), in pancreatic duct lesions adjacent to infiltrating
pancreas cancers in a series of 19 cases of pancreatic duct adenocarcinoma. HER-2/neu …
grades of pancreatic duct hyperplasia as precursor lesions to infiltrating pancreatic
adenocarcinoma, the identity of preinvasive pancreatic neoplasms remains controversial. In
the present study, the authors examined the expression of the epidermal growth factor
receptor homologue, HER-2/neu (c-erbB-2), in pancreatic duct lesions adjacent to infiltrating
pancreas cancers in a series of 19 cases of pancreatic duct adenocarcinoma. HER-2/neu …