The Ras superfamily at a glance

K Wennerberg, KL Rossman… - Journal of cell …, 2005 - journals.biologists.com
Journal of cell science, 2005journals.biologists.com
GXXXXGKS/T; G2, T; G3, DXXGQ/H/T; G4, T/NKXD; and G5, C/SAK/L/T (Bourne et al.,
1991)(Fig. S1 in supplementary material). Together, these elements make up an~ 20 kDa G
domain (Ras residues 5-166) that has a conserved structure and biochemistry shared by all
Ras superfamily proteins, as well as Gα and other GTPases.
GXXXXGKS/T; G2, T; G3, DXXGQ/H/T; G4, T/NKXD; and G5, C/SAK/L/T (Bourne et al., 1991)(Fig. S1 in supplementary material). Together, these elements make up an~ 20 kDa G domain (Ras residues 5-166) that has a conserved structure and biochemistry shared by all Ras superfamily proteins, as well as Gα and other GTPases.
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