An update on the genetics of atopic dermatitis: scratching the surface in 2009
KC Barnes - Journal of Allergy and Clinical Immunology, 2010 - Elsevier
A genetic basis for atopic dermatitis (AD) has long been recognized. Historic documents
allude to family history of disease as a risk factor. Before characterization of the human
genome, heritability studies combined with family-based linkage studies supported the
definition of AD as a complex trait in that interactions between genes and environmental
factors and the interplay between multiple genes contribute to disease manifestation. A
summary of more than 100 published reports on genetic association studies through mid …
allude to family history of disease as a risk factor. Before characterization of the human
genome, heritability studies combined with family-based linkage studies supported the
definition of AD as a complex trait in that interactions between genes and environmental
factors and the interplay between multiple genes contribute to disease manifestation. A
summary of more than 100 published reports on genetic association studies through mid …