A pilot study of emollient therapy for the primary prevention of atopic dermatitis

EL Simpson, TM Berry, PA Brown, JM Hanifin - Journal of the American …, 2010 - Elsevier
BACKGROUND: Prevention strategies in atopic dermatitis (AD) using allergen avoidance
have not been consistently effective. New research reveals the importance of the skin barrier
in the development of AD and possibly food allergy and asthma. Correcting skin barrier
defects from birth may prevent AD onset or moderate disease severity. OBJECTIVE: We
sought to determine the feasibility of skin barrier protection as a novel AD prevention
strategy. METHODS: We enrolled 22 neonates at high risk for developing AD in a feasibility …