Hair follicle stem cells in the lower bulge form the secondary germ, a biochemically distinct but functionally equivalent progenitor cell population, at the termination of …
M Ito, G Cotsarelis, K Kizawa, K Hamada - Differentiation, 2004 - Elsevier
The lowermost portion of the resting (telogen) follicle consists of the bulge and secondary
hair germ. We previously showed that the progeny of stem cells in the bulge form the lower
follicle and hair, but the relationship of the bulge cells with the secondary hair germ cells,
which are also involved in the generation of the new hair at the onset of the hair growth cycle
(anagen), remains unclear. Here we address whether secondary hair germ cells are derived
directly from epithelial stem cells in the adjacent bulge or whether they arise from cells within …
hair germ. We previously showed that the progeny of stem cells in the bulge form the lower
follicle and hair, but the relationship of the bulge cells with the secondary hair germ cells,
which are also involved in the generation of the new hair at the onset of the hair growth cycle
(anagen), remains unclear. Here we address whether secondary hair germ cells are derived
directly from epithelial stem cells in the adjacent bulge or whether they arise from cells within …