Skin barrier function and allergic risk
TJ Hudson - Nature genetics, 2006 - nature.com
TJ Hudson
Nature genetics, 2006•nature.comA new study reports that two common loss-of-function mutations in the gene encoding
filaggrin are important risk factors for atopic dermatitis, and interestingly, for asthma in
association with atopic dermatitis, but not asthma in the absence of atopic dermatitis. These
findings suggest the importance of the epidermal barrier in preventing sensitization to
allergens.
filaggrin are important risk factors for atopic dermatitis, and interestingly, for asthma in
association with atopic dermatitis, but not asthma in the absence of atopic dermatitis. These
findings suggest the importance of the epidermal barrier in preventing sensitization to
allergens.
A new study reports that two common loss-of-function mutations in the gene encoding filaggrin are important risk factors for atopic dermatitis, and interestingly, for asthma in association with atopic dermatitis, but not asthma in the absence of atopic dermatitis. These findings suggest the importance of the epidermal barrier in preventing sensitization to allergens.
nature.com