[HTML][HTML] Fibroblast growth factor-2-mediated capillary morphogenesis of endothelial cells requires signals via Flt-1/vascular endothelial growth factor receptor-1 …
S Kanda, Y Miyata, H Kanetake - Journal of Biological Chemistry, 2004 - ASBMB
Capillary morphogenesis is a crucial angiogenic response of endothelial cells. Although
fibroblast growth factor-2 (FGF-2) potently induces capillary morphogenesis, the contribution
of vascular endothelial growth factor-A (VEGF-A) in this response has not been clarified well.
Here we examined the role of VEGF signaling in FGF-2-induced capillary morphogenesis by
murine brain capillary endothelial cells (IBE cells) and human umbilical vein endothelial
cells. FGF-2-treated IBE cells rapidly extended on Matrigel in association with actin …
fibroblast growth factor-2 (FGF-2) potently induces capillary morphogenesis, the contribution
of vascular endothelial growth factor-A (VEGF-A) in this response has not been clarified well.
Here we examined the role of VEGF signaling in FGF-2-induced capillary morphogenesis by
murine brain capillary endothelial cells (IBE cells) and human umbilical vein endothelial
cells. FGF-2-treated IBE cells rapidly extended on Matrigel in association with actin …