Nuclear lamins and chromatin: when structure meets function

T Dechat, SA Adam, RD Goldman - Advances in enzyme regulation, 2009 - Elsevier
The nucleus of eukaryotic cells can be sub-divided into three main compartments:
chromatin, intranuclear non-membrane bound complexes (which more or less act like
cytoplasmic ''organelles''), and the nuclear envelope (NE)(Schneider and Grosschedl, 2007;
Spector, 2006; Verstraeten et al., 2007). The NE is composed of the outer and inner nuclear
membrane (INM), nuclear pore complexes (NPCs) and the nuclear lamina. The latter is a
proteinaceous meshwork underlying the INM and is connected to NPCs (Aaronson and …