Collagen and elastin fibres are of major importance in providing the aorta with tensile
strength and elasticity. The presence of cross-links in collagen and elastin is essential for the
mechanical stability of collagen and elastin fibres. β-aminopropionitrile (BAPN) reduces the
formation of cross-links by inhibiting the enzyme lysyloxidase. Young rats were injected with
BAPN to inhibit the formation of cross-links, and the changes in the biomechanical and
biochemical properties of the thoracic aorta were studied. The biomechanical analyses of …