Differential expression and dynamic changes of murine NEDD9 in progenitor cells of diverse tissues

JB Aquino, F Marmigère, F Lallemend… - Gene Expression …, 2008 - Elsevier
NEDD9 is a scaffolding protein in the integrin signaling pathway that is involved in cell
adhesion dynamics. Little is known of the cellular localization of NEDD9 expression during
embryonic development. In the present study, we have analyzed NEDD9 mRNA expression
in the mouse and identified new relevant expression sites. In addition, we have
characterized NEDD9 protein expression pattern for the first time in mammals. At E9. 5–E10.
5, high levels of Nedd9 and the neurogenic transcription factor neurogenin-2 (Ngn2) were …