Peanut epitopes for IgE and IgG4 in peanut-sensitized children in relation to severity of peanut allergy
AE Flinterman, EF Knol, DA Lencer, L Bardina… - Journal of allergy and …, 2008 - Elsevier
BACKGROUND: Better understanding of the relationship between antibody response to
peanut and clinical sensitivity might lead to more accurate prognostication. OBJECTIVE: We
sought to investigate peanut-specific IgE and IgG4 epitope diversity in relation to challenge-
defined clinical sensitivity to peanut in a group of peanut-sensitized children. METHODS:
Clinical sensitivity was determined by means of double-blind, placebo-controlled peanut
challenges in 24 sensitized children. Six atopic control subjects were included. Specific IgE …
peanut and clinical sensitivity might lead to more accurate prognostication. OBJECTIVE: We
sought to investigate peanut-specific IgE and IgG4 epitope diversity in relation to challenge-
defined clinical sensitivity to peanut in a group of peanut-sensitized children. METHODS:
Clinical sensitivity was determined by means of double-blind, placebo-controlled peanut
challenges in 24 sensitized children. Six atopic control subjects were included. Specific IgE …