Probiotics in prevention of IgE-associated eczema: a double-blind, randomized, placebo-controlled trial

TR Abrahamsson, T Jakobsson, MF Böttcher… - Journal of Allergy and …, 2007 - Elsevier
BACKGROUND: An altered microbial exposure may underlie the increase of allergic
diseases in affluent societies. Probiotics may alleviate and even prevent eczema in infants.
OBJECTIVE: To prevent eczema and sensitization in infants with a family history of allergic
disease by oral supplementation with the probiotic Lactobacillus reuteri. METHODS: Double-
blind, randomized, placebo-controlled trial, which comprised 232 families with allergic
disease, of whom 188 completed the study. The mothers received L reuteri ATCC 55730 (1× …