Causes and histopathology of ascending aortic disease in children and young adults
D Jain, HC Dietz, GL Oswald, JJ Maleszewski… - Cardiovascular …, 2011 - Elsevier
BACKGROUND: Ascending aortic diseases (aneurysms, dissections, and stenosis) and
associated aortic valve disease are rare but important causes of morbidity and mortality in
children and young adults. Certain genetic causes, such as Marfan syndrome and
congenital bicuspid aortic valve disease, are well known. However, other rarer genetic and
nongenetic causes of aortic disease exist. METHODS: We performed an extensive literature
search to identify known causes of ascending aortic pathology in children and young adults …
associated aortic valve disease are rare but important causes of morbidity and mortality in
children and young adults. Certain genetic causes, such as Marfan syndrome and
congenital bicuspid aortic valve disease, are well known. However, other rarer genetic and
nongenetic causes of aortic disease exist. METHODS: We performed an extensive literature
search to identify known causes of ascending aortic pathology in children and young adults …