Generation of mutant mice lacking surface expression of CD4 or CD8 gene targeting

TW Mak, A Rahemtulla, M Schilham, DR Koh… - … of Lymphocyte Activation …, 1992 - Springer
TW Mak, A Rahemtulla, M Schilham, DR Koh, WP Fung-Leung
Mechanisms of Lymphocyte Activation and Immune Regulation IV: Cellular …, 1992•Springer
With the use of homologous recombination in embryonic stem cells, two new strains of mice
lacking surface CD4 or CDS expression have been generated. It is hoped that they will be
useful mouse strains for the study of autoimmune diseases, tissue transplantation rejections
and tumour rejections.
Abstract
With the use of homologous recombination in embryonic stem cells, two new strains of mice lacking surface CD4 or CDS expression have been generated. It is hoped that they will be useful mouse strains for the study of autoimmune diseases, tissue transplantation rejections and tumour rejections.
Springer
Show moreShow less
Save Cite Cited by 28 Related articles All 14 versions