Atheroprotective effects of high-density lipoprotein-associated lysosphingolipids
JR Nofer, G Assmann - Trends in cardiovascular medicine, 2005 - Elsevier
Numerous epidemiological studies document an inverse relationship between plasma high-
density lipoprotein (HDL) levels and the extent of atherosclerotic disease. The
atheroprotective effects of HDL are more and more often seen in conjunction with the ability
of HDL to restrict proinflammatory processes and thereby to carry out cytoprotection and
organoprotection. Lysosphingolipids such as sphingosine 1 phosphate,
sphingosylphosphorylcholine, and lysosulfatide are biologically active compounds that have …
density lipoprotein (HDL) levels and the extent of atherosclerotic disease. The
atheroprotective effects of HDL are more and more often seen in conjunction with the ability
of HDL to restrict proinflammatory processes and thereby to carry out cytoprotection and
organoprotection. Lysosphingolipids such as sphingosine 1 phosphate,
sphingosylphosphorylcholine, and lysosulfatide are biologically active compounds that have …