A Sertoli cell-specific knock-out of the androgen receptor.
G Verhoeven - Andrologia, 2005 - search.ebscohost.com
G Verhoeven
Andrologia, 2005•search.ebscohost.comThe article cites a study which explores the relative contribution of Sertoli cells to androgen
action. This study aims to determine the cellular and molecular mechanisms by which
androgens affect germ cell development. The researchers of this study have generated
transgenic mice with a ubiquitous knockout of the androgen receptor (ARKO) using Cre/loxP
technology.
action. This study aims to determine the cellular and molecular mechanisms by which
androgens affect germ cell development. The researchers of this study have generated
transgenic mice with a ubiquitous knockout of the androgen receptor (ARKO) using Cre/loxP
technology.
Abstract
The article cites a study which explores the relative contribution of Sertoli cells to androgen action. This study aims to determine the cellular and molecular mechanisms by which androgens affect germ cell development. The researchers of this study have generated transgenic mice with a ubiquitous knockout of the androgen receptor (ARKO) using Cre/loxP technology.
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