Prior statin use is associated with improved outcomes in community-acquired pneumonia

JD Chalmers, A Singanayagam, MP Murray… - The American journal of …, 2008 - Elsevier
BACKGROUND: Statins have potent anti-inflammatory effects in laboratory studies of
pulmonary inflammation. We investigated whether statin users had improved outcome when
admitted with community-acquired pneumonia. METHODS: We carried out a prospective
observational study of patients admitted to the hospital with community-acquired pneumonia
between January 2005 and November 2007. The use of statins, angiotensin-converting
enzyme inhibitors, beta-blockers, and aspirin were recorded. The outcomes of interest were …