Normal mammalian muscle differentiation and gene control of isocitrate dehydrogenase synthesis.
B Mintz, WW Baker - … of the National Academy of Sciences, 1967 - National Acad Sciences
B Mintz, WW Baker
Proceedings of the National Academy of Sciences, 1967•National Acad SciencesFIG. 1.-Diagram of expected isozyme results in allophenic mice, on the" division"(left) vs."
fusion"(right) models of skeletal muscle development. When homozygous cellsof different
NADP-isocitrate dehydrogenase genotypes coexist, heterokaryons would resultin the event
of myoblast fusion, and hybrid enzyme could be formed. Enzyme molecules are represented
as dimers formed inl the cytoplasm from polypeptide subunits (see text).
fusion"(right) models of skeletal muscle development. When homozygous cellsof different
NADP-isocitrate dehydrogenase genotypes coexist, heterokaryons would resultin the event
of myoblast fusion, and hybrid enzyme could be formed. Enzyme molecules are represented
as dimers formed inl the cytoplasm from polypeptide subunits (see text).
FIG. 1.-Diagram of expected isozyme results in allophenic mice, on the" division"(left) vs." fusion"(right) models of skeletal muscle development. When homozygous cellsof different NADP-isocitrate dehydrogenase genotypes coexist, heterokaryons would resultin the event of myoblast fusion, and hybrid enzyme could be formed. Enzyme molecules are represented as dimers formed inl the cytoplasm from polypeptide subunits (see text).
National Acad Sciences