[CITATION][C] Function and regulation of collecting duct intercalated cells
VL Schuster - Annual review of physiology, 1993 - annualreviews.org
Renal intercalated cells (IC) are interspersed among the segment-specific majority
(principal) cells of the distal convoluted tubule, connecting tubule, and collecting duct (71,
144). Ultrastructurally, ICs are distinguished by their dark cytoplasm, high mitochondrial
density, cytoplasmic tubulovesicular structures, and apical microprojections (87). There are
two major collecting duct IC SUbtypes, and they mediate H+ and HC03 secretion, and CI
and K+ reabsorption (116-119, 123). This review focuses on immunocytochemistry and …
(principal) cells of the distal convoluted tubule, connecting tubule, and collecting duct (71,
144). Ultrastructurally, ICs are distinguished by their dark cytoplasm, high mitochondrial
density, cytoplasmic tubulovesicular structures, and apical microprojections (87). There are
two major collecting duct IC SUbtypes, and they mediate H+ and HC03 secretion, and CI
and K+ reabsorption (116-119, 123). This review focuses on immunocytochemistry and …