Learning Objectives After completing this course, the reader will be able to: Describe the
pathways involved in the natural resistance of cancer cells to cytotoxic insults including radio-
/chemotherapy. Explain autophagic cell death as a potent alternative tumor-suppressing
mechanism. Identify the common targets in apoptosis and autophagy resistance pathways
and the surrogate markers that could be used in clinical practice for proautophagic therapy.
Discuss the rationale for incorporating endoplasmic reticulum stress inhibitors as adjuvant …