A Proteomic Analysis of Human Cilia: Identification of Novel Components* S
LE Ostrowski, K Blackburn, KM Radde… - Molecular & Cellular …, 2002 - ASBMB
Cilia play an essential role in protecting the respiratory tract by providing the force necessary
for mucociliary clearance. Although the major structural components of human cilia have
been described, a complete understanding of cilia function and regulation will require
identification and characterization of all ciliary components. Estimates from studies of
Chlamydomonas flagella predict that an axoneme contains≥ 250 proteins. To identify all the
components of human cilia, we have begun a comprehensive proteomic analysis of isolated …
for mucociliary clearance. Although the major structural components of human cilia have
been described, a complete understanding of cilia function and regulation will require
identification and characterization of all ciliary components. Estimates from studies of
Chlamydomonas flagella predict that an axoneme contains≥ 250 proteins. To identify all the
components of human cilia, we have begun a comprehensive proteomic analysis of isolated …
