It's all about sex: gender, lung development and lung disease
MA Carey, JW Card, JW Voltz, SJ Arbes… - Trends in Endocrinology …, 2007 - cell.com
MA Carey, JW Card, JW Voltz, SJ Arbes, DR Germolec, KS Korach, DC Zeldin
Trends in Endocrinology & Metabolism, 2007•cell.comAccumulating evidence suggests that gender affects the incidence, susceptibility and
severity of several lung diseases. Gender also influences lung development and physiology.
Data from both human and animal studies indicate that sex hormones might contribute to
disease pathogenesis or serve as protective factors, depending on the disease involved. In
this review, the influence of gender and sex hormones on lung development and pathology
will be discussed, with specific emphasis on pulmonary fibrosis, asthma and cancer.
severity of several lung diseases. Gender also influences lung development and physiology.
Data from both human and animal studies indicate that sex hormones might contribute to
disease pathogenesis or serve as protective factors, depending on the disease involved. In
this review, the influence of gender and sex hormones on lung development and pathology
will be discussed, with specific emphasis on pulmonary fibrosis, asthma and cancer.
Accumulating evidence suggests that gender affects the incidence, susceptibility and severity of several lung diseases. Gender also influences lung development and physiology. Data from both human and animal studies indicate that sex hormones might contribute to disease pathogenesis or serve as protective factors, depending on the disease involved. In this review, the influence of gender and sex hormones on lung development and pathology will be discussed, with specific emphasis on pulmonary fibrosis, asthma and cancer.
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