Dendritic cells (DCs) are professional antigen-presenting cells that have the ability to sense
infection and tissue stress, sample and present antigen to T lymphocytes, and induce
different forms of immunity and tolerance. The functional versatility of DCs depends on their
remarkable ability to translate collectively the information from both the invading microbes
and their resident tissue microenvironments and then make an appropriate immune
response. Recent progress in understanding TLR biology has illuminated the mechanisms …