[HTML][HTML] Liver fatty acid-binding protein initiates budding of pre-chylomicron transport vesicles from intestinal endoplasmic reticulum
I Neeli, SA Siddiqi, S Siddiqi, J Mahan… - Journal of Biological …, 2007 - ASBMB
The rate-limiting step in the transit of absorbed dietary fat across the enterocyte is the
generation of the pre-chylomicron transport vesicle (PCTV) from the endoplasmic reticulum
(ER). This vesicle does not require coatomer-II (COPII) proteins for budding from the ER
membrane and contains vesicle-associated membrane protein 7, found in intestinal ER,
which is a unique intracellular location for this SNARE protein. We wished to identify the
protein (s) responsible for budding this vesicle from ER membranes in the absence of the …
generation of the pre-chylomicron transport vesicle (PCTV) from the endoplasmic reticulum
(ER). This vesicle does not require coatomer-II (COPII) proteins for budding from the ER
membrane and contains vesicle-associated membrane protein 7, found in intestinal ER,
which is a unique intracellular location for this SNARE protein. We wished to identify the
protein (s) responsible for budding this vesicle from ER membranes in the absence of the …