Defective presentation to class I-restricted cytotoxic T lymphocytes in vaccinia-infected cells is overcome by enhanced degradation of antigen.
A Townsend, J Bastin, K Gould, G Brownlee… - Journal of Experimental …, 1988 - rupress.org
A Townsend, J Bastin, K Gould, G Brownlee, M Andrew, B Coupar, D Boyle, S Chan…
Journal of Experimental Medicine, 1988•rupress.orgMaterials and Methods Mice. 3-6-mo-old C57BL/10 or CBA mice used as responding cell
donors were obtained from the National Institute for Medical Research, London, UK, or the
Sir William Dunn School of Pathology, Oxford, UK In Vivo Priming ofMice. Mice were
anesthetized with ether and primed by intranasal infection with five haemagglutinin units
(HAU) of E61-13-H17 influenza virus as infectious allantoic fluid diluted in 50 al PBS (16), or
by intravenous injection of 10'PFU recombinant HlVAC, 7. 5K as described (17).
donors were obtained from the National Institute for Medical Research, London, UK, or the
Sir William Dunn School of Pathology, Oxford, UK In Vivo Priming ofMice. Mice were
anesthetized with ether and primed by intranasal infection with five haemagglutinin units
(HAU) of E61-13-H17 influenza virus as infectious allantoic fluid diluted in 50 al PBS (16), or
by intravenous injection of 10'PFU recombinant HlVAC, 7. 5K as described (17).
Materials and Methods
Mice. 3-6-mo-old C57BL/10 or CBA mice used as responding cell donors were obtained from the National Institute for Medical Research, London, UK, or the Sir William Dunn School of Pathology, Oxford, UK
In Vivo Priming ofMice. Mice were anesthetized with ether and primed by intranasal infection with five haemagglutinin units (HAU) of E61-13-H17 influenza virus as infectious allantoic fluid diluted in 50 al PBS (16), or by intravenous injection of 10'PFU recombinant HlVAC, 7. 5K as described (17).
rupress.org