Synaptobrevin 2 is palmitoylated in synaptic vesicles prepared from adult, but not from embryonic brain
M Veit, A Becher, G Ahnert-Hilger - Molecular and Cellular Neuroscience, 2000 - Elsevier
Neuronal SNARE-proteins such as synaptobrevin, SNAP 25, and synaptotagmin are key
players during neurosecretion. So far palmitoylation of SNAP-25 and synaptotagmin 1 have
been described in vivo. Here we have analyzed palmitoylation of the SNARE-proteins
synaptobrevin 2 and synaptotagmin in vitro using synaptosomal and synaptic vesicle
preparations from rat brain. Labeling of synaptic vesicles prepared from adult brain with [3H]
palmitate revealed synaptobrevin 2 besides synaptotagmin 1 as major palmitoylated …
players during neurosecretion. So far palmitoylation of SNAP-25 and synaptotagmin 1 have
been described in vivo. Here we have analyzed palmitoylation of the SNARE-proteins
synaptobrevin 2 and synaptotagmin in vitro using synaptosomal and synaptic vesicle
preparations from rat brain. Labeling of synaptic vesicles prepared from adult brain with [3H]
palmitate revealed synaptobrevin 2 besides synaptotagmin 1 as major palmitoylated …
