Nitric oxide metabolites in CSF of patients with MS are related to clinical disease course
A Svenningsson, AS Petersson, O Andersen… - Neurology, 1999 - AAN Enterprises
A Svenningsson, AS Petersson, O Andersen, GK Hansson
Neurology, 1999•AAN EnterprisesArticle abstract In this study, we have analyzed the stable metabolites of nitric oxide (NO),
nitrite and nitrate, in the CSF of patients with MS, lymphocytic meningitis, and in healthy
control subjects. Patients with MS with an active disease course exhibited increased CSF
nitrite levels compared with patients with stable MS and healthy control subjects, whereas
CSF nitrate levels did not differ between these groups. High CSF levels of both metabolites
were seen in patients with meningitis. These data indicate that CSF nitrite levels may reflect …
nitrite and nitrate, in the CSF of patients with MS, lymphocytic meningitis, and in healthy
control subjects. Patients with MS with an active disease course exhibited increased CSF
nitrite levels compared with patients with stable MS and healthy control subjects, whereas
CSF nitrate levels did not differ between these groups. High CSF levels of both metabolites
were seen in patients with meningitis. These data indicate that CSF nitrite levels may reflect …
Article abstract In this study, we have analyzed the stable metabolites of nitric oxide (NO), nitrite and nitrate, in the CSF of patients with MS, lymphocytic meningitis, and in healthy control subjects. Patients with MS with an active disease course exhibited increased CSF nitrite levels compared with patients with stable MS and healthy control subjects, whereas CSF nitrate levels did not differ between these groups. High CSF levels of both metabolites were seen in patients with meningitis. These data indicate that CSF nitrite levels may reflect clinical disease activity in MS.
American Academy of Neurology