Improved methods for building protein models in electron density maps and the location of errors in these models
TA Jones, JY Zou, SWT Cowan… - … Section A: Foundations …, 1991 - scripts.iucr.org
TA Jones, JY Zou, SWT Cowan, M Kjeldgaard
Acta Crystallographica Section A: Foundations of Crystallography, 1991•scripts.iucr.orgMap interpretation remains a critical step in solving the structure of a macromolecule. Errors
introduced at this early stage may persist throughout crystallographic refinement and result
in an incorrect structure. The normally quoted crystallographic residual is often a poor
description for the quality of the model. Strategies and tools are described that help to
alleviate this problem. These simplify the model-building process, quantify the goodness of
fit of the model on a per-residue basis and locate possible errors in peptide and side-chain …
introduced at this early stage may persist throughout crystallographic refinement and result
in an incorrect structure. The normally quoted crystallographic residual is often a poor
description for the quality of the model. Strategies and tools are described that help to
alleviate this problem. These simplify the model-building process, quantify the goodness of
fit of the model on a per-residue basis and locate possible errors in peptide and side-chain …
Map interpretation remains a critical step in solving the structure of a macromolecule. Errors introduced at this early stage may persist throughout crystallographic refinement and result in an incorrect structure. The normally quoted crystallographic residual is often a poor description for the quality of the model. Strategies and tools are described that help to alleviate this problem. These simplify the model-building process, quantify the goodness of fit of the model on a per-residue basis and locate possible errors in peptide and side-chain conformations.
International Union of Crystallography