[HTML][HTML] Mitogenic signal transduction by integrin-and growth factor receptor-mediated pathways
JW Lee, R Juliano - Molecules and cells, 2004 - Elsevier
Engagement of cells with the extracellular matrix (ECM) proteins is crucial for various
biological processes, including cell adhesion, spreading, proliferation, differentiation,
migration, apoptosis, and gene induction, contributing to maintenance of tissue integrity,
embryogenesis, wound healing, and the metastasis of tumor cells (Hynes, 2002b; Juliano,
2002). The engagement involves cell adhesion mediated by integrins, a large family of cell
adhesion receptors that are transmembrane glycoproteins which bind to ECM or to counter …
biological processes, including cell adhesion, spreading, proliferation, differentiation,
migration, apoptosis, and gene induction, contributing to maintenance of tissue integrity,
embryogenesis, wound healing, and the metastasis of tumor cells (Hynes, 2002b; Juliano,
2002). The engagement involves cell adhesion mediated by integrins, a large family of cell
adhesion receptors that are transmembrane glycoproteins which bind to ECM or to counter …
