The expression of iASPP in acute leukemias
X Zhang, M Wang, C Zhou, S Chen, J Wang - Leukemia research, 2005 - Elsevier
Inhibitory member of the ASPP family (iASPP) is an evolutionarily conserved inhibitor of p53,
and its expression is upregulated in human breast carcinomas expressing wild-type p53. To
examine the role of iASPP in acute leukemia (AL), we analyzed iASPP mRNA expression in
AL by semi-quantitative reverse transcriptase polymerase chain reaction (RT-PCR). PCR
products were confirmed by restriction endonuclease BstX I digestion and sequencing
analysis. The results showed that median levels of iASPP gene expression in cells of AL …
and its expression is upregulated in human breast carcinomas expressing wild-type p53. To
examine the role of iASPP in acute leukemia (AL), we analyzed iASPP mRNA expression in
AL by semi-quantitative reverse transcriptase polymerase chain reaction (RT-PCR). PCR
products were confirmed by restriction endonuclease BstX I digestion and sequencing
analysis. The results showed that median levels of iASPP gene expression in cells of AL …