[HTML][HTML] A monoclonal antibody to glucosylceramide inhibits the growth of Fonsecaea pedrosoi and enhances the antifungal action of mouse macrophages

L Nimrichter, E Barreto-Bergter… - Microbes and …, 2004 - Elsevier
Fungal glucosylceramides (GlcCer) are conserved lipid components in a large variety of
pathogenic and non-pathogenic fungal species, but their biological functions are still
unclear. Recent studies demonstrate that GlcCer are immunologically active components
inducing the production of antifungal antibodies. In this work, a major GlcCer was purified
and characterized from mycelial forms of Fonsecaea pedrosoi, the most frequent causative
agent of chromoblastomycosis. As determined by fast atom bombardment mass …