[HTML][HTML] Glucosylceramide synthases, a gene family responsible for the biosynthesis of glucosphingolipids in animals, plants, and fungi

M Leipelt, D Warnecke, U Zähringer, C Ott… - Journal of Biological …, 2001 - ASBMB
Glucosylceramides are membrane lipids in most eukaryotic organisms and in a few bacteria.
The physiological functions of these glycolipids have only been documented in mammalian
cells, whereas very little information is available of their roles in plants, fungi, and bacteria. In
an attempt to establish appropriate experimental systems to study glucosylceramide
functions in these organisms, we performed a systematic functional analysis of a
glycosyltransferase gene family with members of animal, plant, fungal, and bacterial origin …