αvβ3 and αvβ5 integrin expression in glioma periphery
L Bello, M Francolini, P Marthyn, J Zhang… - …, 2001 - journals.lww.com
OBJECTIVE: This study analyzed the expression of integrins αvβ3 and αvβ5 in glioma tissue
and focused on the periphery of high-grade gliomas. METHODS: The analysis was
performed with Western blot, immunohistochemistry, and immunofluorescence, by use of
two monoclonal antibodies able to recognize the functional integrin heterodimer. The
expression of integrin-related ligands and growth factors also was studied. Sections from the
tumor periphery were classified as either tumor periphery (light tumor infiltrate or scant …
and focused on the periphery of high-grade gliomas. METHODS: The analysis was
performed with Western blot, immunohistochemistry, and immunofluorescence, by use of
two monoclonal antibodies able to recognize the functional integrin heterodimer. The
expression of integrin-related ligands and growth factors also was studied. Sections from the
tumor periphery were classified as either tumor periphery (light tumor infiltrate or scant …