Types of cell death include apoptosis, necrosis, and autophagic cell death. The latter can be
defined as death of cells containing autophagosomes, autophagic bodies, and/or vacuoles.
Are autophagy and vacuolization causes, consequences, or side effects in cell death with
autophagy? Would control of autophagy suffice to control this type of cell death? We
disrupted the atg1 autophagy gene in Dictyostelium discoideum, a genetically tractable
model for developmental autophagic vacuolar cell death. The procedure that induced …