Regulation of endocytic traffic by rho family GTPases
S Ellis, H Mellor - Trends in cell biology, 2000 - cell.com
S Ellis, H Mellor
Trends in cell biology, 2000•cell.comEndocytosis is a complicated yet highly efficient process that involves the uptake and
processing of cargoes, ranging from small molecules, to activated signalling receptors, to
whole microorganisms. Regulation of endocytic pathways is poorly understood. Recent
evidence suggests that the Rho GTPase family of signalling proteins is intimately involved in
endocytic traffic, providing novel insights into the control mechanisms that govern this
process.
processing of cargoes, ranging from small molecules, to activated signalling receptors, to
whole microorganisms. Regulation of endocytic pathways is poorly understood. Recent
evidence suggests that the Rho GTPase family of signalling proteins is intimately involved in
endocytic traffic, providing novel insights into the control mechanisms that govern this
process.
Abstract
Endocytosis is a complicated yet highly efficient process that involves the uptake and processing of cargoes, ranging from small molecules, to activated signalling receptors, to whole microorganisms. Regulation of endocytic pathways is poorly understood. Recent evidence suggests that the Rho GTPase family of signalling proteins is intimately involved in endocytic traffic, providing novel insights into the control mechanisms that govern this process.
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