Trefoil proteins: their role in normal and malignant cells
FEB May, BR Westley - The Journal of Pathology: A Journal of …, 1997 - Wiley Online Library
FEB May, BR Westley
The Journal of Pathology: A Journal of the Pathological Society of …, 1997•Wiley Online LibraryThe three human trefoil proteins pS2, human intestinal trefoil factor (hITF), and human
spasmolytic polypeptide (hSP) are expressed principally in the mucosa of the
gastrointestinal tract. They are also expressed in a variety of other normal tissues and
tumours. This review discusses the pattern of expression of trefoil proteins in cancer, current
views on the biological functions of trefoil proteins, and the way in which the expression of
trefoil proteins may influence the behaviour of cancer cells.© 1997 by John Wiley & Sons …
spasmolytic polypeptide (hSP) are expressed principally in the mucosa of the
gastrointestinal tract. They are also expressed in a variety of other normal tissues and
tumours. This review discusses the pattern of expression of trefoil proteins in cancer, current
views on the biological functions of trefoil proteins, and the way in which the expression of
trefoil proteins may influence the behaviour of cancer cells.© 1997 by John Wiley & Sons …
Abstract
The three human trefoil proteins pS2, human intestinal trefoil factor (hITF), and human spasmolytic polypeptide (hSP) are expressed principally in the mucosa of the gastrointestinal tract. They are also expressed in a variety of other normal tissues and tumours. This review discusses the pattern of expression of trefoil proteins in cancer, current views on the biological functions of trefoil proteins, and the way in which the expression of trefoil proteins may influence the behaviour of cancer cells. © 1997 by John Wiley & Sons, Ltd.
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