Right ventricular cardiac dysfunction in β-thalassemia major

A Koren, I Garty, D Antonelli… - American Journal of …, 1987 - jamanetwork.com
• In patients with iron overload associated with severe, transfusion-dependent β-
thalassemia, congestive heart failure develops during the second decade of life.
Biventricular heart function Was studied by multigated radionuclide angiography In 22
patients with β-thalassemia major. Six patients were symptomatic. Congestive heart failure
developed in five patients at the time of blood transfusions, and one other patient had been
treated for multiple ventricular extrasystole. The mean (±SD) left ventricular ejection fraction …