Understanding the timing of HIV transmission from mother to infant

AP Kourtis, M Bulterys, SR Nesheim, FK Lee - Jama, 2001 - jamanetwork.com
MOTHER-TO-INFANT TRANSMIS-sion of human immunodeficiency virus (HIV) occurs,
without any intervention, at rates of 14% to 42% in various settings. 1, 2 Determining the
timing of such transmission is of great clinical relevance for implementing cost-effective
prophylaxis. 3, 4 Based on virologic detection of HIV during the infant's first 2 days of life, it is
generally accepted that about one third of transmissions in nonbreastfeeding women occur
during gestation and the remaining two thirds during delivery. 5-9 Further support for the …