Selective gamma-chain T-cell receptor gene rearrangements in a patient with Omenn's syndrome: absence of V-II subgroup (V gamma 9) transcripts
G Mathioudakis, RA Good… - Clinical Diagnostic …, 1996 - Am Soc Microbiol
G Mathioudakis, RA Good, Y Chernajovsky, NK Day, CD Platsoucas
Clinical Diagnostic Laboratory Immunology, 1996•Am Soc MicrobiolOnly gamma-chain T-cell receptor transcripts utilizing V-1 subgroup gene segments were
found in peripheral blood lymphocytes from a patient with Omenn's syndrome. gamma-
Chain T-cell receptor transcripts utilizing the V gamma 9 (V-II subgroup) gene segment were
absent in peripheral blood lymphocytes from this patient. V gamma 9 J gamma 1.2 C gamma
1 rearrangements are those primarily found in peripheral blood lymphocytes (70 to 85%)
from normal donors.
found in peripheral blood lymphocytes from a patient with Omenn's syndrome. gamma-
Chain T-cell receptor transcripts utilizing the V gamma 9 (V-II subgroup) gene segment were
absent in peripheral blood lymphocytes from this patient. V gamma 9 J gamma 1.2 C gamma
1 rearrangements are those primarily found in peripheral blood lymphocytes (70 to 85%)
from normal donors.
Only gamma-chain T-cell receptor transcripts utilizing V-1 subgroup gene segments were found in peripheral blood lymphocytes from a patient with Omenn's syndrome. gamma-Chain T-cell receptor transcripts utilizing the V gamma 9 (V-II subgroup) gene segment were absent in peripheral blood lymphocytes from this patient. V gamma 9 J gamma 1.2 C gamma 1 rearrangements are those primarily found in peripheral blood lymphocytes (70 to 85%) from normal donors.
American Society for Microbiology