Induction of apoptosis after stent implantation in canine portal vein
FA Kudo, T Nishibe, K Miyazaki, S Watanabe… - Annals of vascular …, 2002 - Elsevier
The purpose of this study was to analyze apoptosis in the vessel wall after stent implantation
in the canine portal vein and also to investigate the expression of the p21 cyclin-dependent
kinase inhibitor, which may regulate cellular proliferation after vascular injury. Uninjured,
control veins had few detectable TUNEL-positive cells in the intima and media
(0.829±0.413%). At 4 weeks after stent implantation, TUNEL-positive cells significantly
increased to 50.5±4.639%. These cells were predominantly located around the stent struts …
in the canine portal vein and also to investigate the expression of the p21 cyclin-dependent
kinase inhibitor, which may regulate cellular proliferation after vascular injury. Uninjured,
control veins had few detectable TUNEL-positive cells in the intima and media
(0.829±0.413%). At 4 weeks after stent implantation, TUNEL-positive cells significantly
increased to 50.5±4.639%. These cells were predominantly located around the stent struts …