[HTML][HTML] Functional activity of murine CD34+ and CD34− hematopoietic stem cell populations
DS Donnelly, D Zelterman, S Sharkis… - Experimental hematology, 1999 - Elsevier
The transmembrane glycoprotein CD34 is expressed on human hematopoietic stem cells
and committed progenitors in the bone marrow, and CD34-positive selection currently is
used to isolate bone marrow repopulating cells in clinical transplantation protocols.
Recently, CD34− hematopoietic stem cells were described in both humans and mice, and it
was suggested that CD34+ murine bone marrow cells may lack long-term reconstituting
ability. In this study, the long-term repopulating ability of CD34+ Lin− vs CD34− Lin− cells …
and committed progenitors in the bone marrow, and CD34-positive selection currently is
used to isolate bone marrow repopulating cells in clinical transplantation protocols.
Recently, CD34− hematopoietic stem cells were described in both humans and mice, and it
was suggested that CD34+ murine bone marrow cells may lack long-term reconstituting
ability. In this study, the long-term repopulating ability of CD34+ Lin− vs CD34− Lin− cells …