Clinical outcome in pneumococcal meningitis correlates with CSF lipoteichoic acid concentrations

O Schneider, U Michel, G Zysk, O Dubuis, R Nau - Neurology, 1999 - AAN Enterprises
O Schneider, U Michel, G Zysk, O Dubuis, R Nau
Neurology, 1999AAN Enterprises
Article abstract Lipoteichoic and teichoic acids are components of the cell wall of
Streptococcus pneumoniae. A recently developed enzyme immunoassay was used in
patients with pneumococcal meningitis to investigate lipoteichoic and teichoic acid
concentrations in CSF at the first lumbar puncture in relation to the clinical outcome
determined by the Glasgow Outcome Scale. Lipoteichoic and teichoic acid concentrations in
CSF were significantly associated with neurologic sequelae and mortality in S. pneumoniae …
Article abstract Lipoteichoic and teichoic acids are components of the cell wall of Streptococcus pneumoniae. A recently developed enzyme immunoassay was used in patients with pneumococcal meningitis to investigate lipoteichoic and teichoic acid concentrations in CSF at the first lumbar puncture in relation to the clinical outcome determined by the Glasgow Outcome Scale. Lipoteichoic and teichoic acid concentrations in CSF were significantly associated with neurologic sequelae and mortality in S. pneumoniae meningitis.
American Academy of Neurology