Airway inflammation is a hallmark of respiratory diseases such as asthma and chronic
obstructive pulmonary disease. Cell adhesion molecules play critical roles in the recruitment
and migration of cells to sites of inflammation. Not surprisingly, these receptors have
garnered the attention of the pharmaceutical industry as targets for the development of drugs
to treat inflammatory and autoimmune diseases. Although several potential cell adhesion
targets exist, development of compounds for pulmonary indications has centered around the …