Fate of H2-activated T lymphocytes in syngeneic hosts: III. Differentiation into long-lived recirculating memory cells
J Sprent, J Miller - Cellular Immunology, 1976 - Elsevier
Memory to H2 determinants was studied with an adoptive transfer system using a population
of H2-activated blast T cells (T. TDL) obtained from thoracic duct lymph of irradiated F 1
hybrid mice injected with parental strain T cells. CBA T. TDL activated either to DBA/2 or
C57BL determinants were transferred to syngeneic “B” mice. Thoracic duct lymphocytes
(TDL) were obtained from the recipients 4–6 weeks later and tested for their capacity to
produce (a) a graft-versus-host (GVH) reaction,(b) a mixed lymphocyte reaction …
of H2-activated blast T cells (T. TDL) obtained from thoracic duct lymph of irradiated F 1
hybrid mice injected with parental strain T cells. CBA T. TDL activated either to DBA/2 or
C57BL determinants were transferred to syngeneic “B” mice. Thoracic duct lymphocytes
(TDL) were obtained from the recipients 4–6 weeks later and tested for their capacity to
produce (a) a graft-versus-host (GVH) reaction,(b) a mixed lymphocyte reaction …