Familial occurrence of dementia with Lewy bodies
DW Tsuang, L DiGiacomo, TD Bird - The American journal of geriatric …, 2004 - Elsevier
Objective The authors investigated the validity of the designation “familial dementia with
Lewy bodies (DLB)” by evaluating the clinical, neuropathological, and genetic
characteristics of previously reported families exhibiting both familial parkinsonism and
dementia. Methods Several families, including multiple individuals with parkinsonism as well
as prominent dementia, were identified through a literature search. Selected families had at
least one member with dementia with autopsy evidence of neocortical and/or limbic Lewy …
Lewy bodies (DLB)” by evaluating the clinical, neuropathological, and genetic
characteristics of previously reported families exhibiting both familial parkinsonism and
dementia. Methods Several families, including multiple individuals with parkinsonism as well
as prominent dementia, were identified through a literature search. Selected families had at
least one member with dementia with autopsy evidence of neocortical and/or limbic Lewy …